TRANSLATIONAL ASPECTS OF NEURODEGENERATION: mechanisms, biomarkers and therapies
November 26 e 27, 2026 • INOVATECA, Parque Tecnológico da UFRJ • Rio de Janeiro, RJ, Brazil
With the aim of bringing together internationally renowned researchers working on different aspects of neurodegenerative diseases, the workshop seeks to create a discussion forum among highly recognized experts in order to understand the molecular mechanisms underlying these aging-related disorders, with a focus on the clinical applicability of this knowledge.
ORGANIZERS
Elis Eleutherio |
IQ - UFRJ, Brazil
Fernanda de Mello e Souza Valente Gubert |
Instituto de Ciências Biomédicas (ICB) – UFRJ, Brazil
Tiago Outeiro |
University Medical Center Göttingen, Germany
PROGRAMMING | SPEAKERS
DAY 1 | NOV 26 / 2026
9h -10h | Registration
10h - 10h30 | Opening Ceremony
Charles Boone
Daniel Jarosz
Henning Ulrich
Session 1: Mechanisms of neurodegeneration: protein assemblies and proteostasis
10h30 - 11h
Tiago Outeiro (U. Goettingen, Germany)
Talk Novel insights into the biology and pathobiology of alpha-synuclein
11h - 11h30
Elis Eleutherio (UFRJ, Brazil)
Talk SOD1: From Neural Biochemistry to Amyotrophic Lateral Sclerosis
11h30 – 12h
Flaviano Giorgini (U. Leicester, UK)
Talk New ways of targeting mitochondrial dysfunction in Huntington's disease
12h - 13h | Lunch
Daniel Kaganovich
Daniel Kaganovich
The Alexander Silbermana Institute of Life Sciences, Jerusalem/ Georg-August-Universität Göttingen, Germany
Harm Kampinga
Andrew Dillin
Session 2: RNA binding proteins and RNA metabolism in neurodegeneration
13h - 13h30
Simon Alberti (Dresden University Technology)
Talk The Dark Side of Biomolecular Condensates:
From Cellular Organisation to Neurodegeneration
13h30- 14h | Oral presentation of selected abstracts
14h - 14h30 | Coffee break
Session 3: Neuron inflammation and immune system responses in neurodegeneration
14h30 – 15h
Malu Tansey (Indiana University, USA)
Talk Immune State versus Immune Trait: A Framework for
Restorative Immunology in Neurodegeneration
15h - 15h30
Talk Glia across the lifespan: shaping the aging brain
15h30 -16h | Oral presentation of selected abstracts
DAY 2 | NOV 27
Session 4: Molecular mechanisms and emerging models of neurodegeneration
Mauricio M Marquez
9h - 9h30
Kay Double (U. Sydney, Australia)
Talk Superoxide dismutase 1 in Parkinson disease: significance and opportunities
9h30-10h
Rosalia Mendez-Otero (UFRJ, Brazil)
Talk New models to study ALS in the Brazilian population
10h - 10h30
Christian Griesinger (Max Planck, Germany)
Talk Structure based mechanistic insights on neurodegeneration and –
protection in aSyn aggregopathies
10h30 - 11h
Henning Ulrich (USP, Brazil))
Talk Extracellular Nucleotide Signaling: The Purinergic Link to Neurogenesis
and Neurodegeneration
11h -13h | Poster session
13h - 14h | Lunch
Session 5: Novel targets and emerging therapeutic opportunities
14h -14h30
Eduardo Rigon Zimmer (UFRS, Brazil)
Talk Targerting astrocytes in neurodegeneration
14h30 -15h
Simone Engelender (Technion, Israel)
Talk SUMOylated α-Synuclein: Mechanisms, Therapeutic Targeting,
and In Vivo Disease Modeling
15h -15h30 | Oral presentation of selected abstracts
15h30 -16h | Coffee break
16h - 16h30 | Panel discussion – Challenges and opportunities
16h30 -17h | Closing ceremony
EXHIBITORS AND SPONSORS
CONTACT
Professor Elis Eleutherio
Phone: + 55 21 3938.7735
FAX: +55 21 3938.7826
Department of Biochemistry
Institute of Chemistry
Universidade Federal do Rio de Janeiro (UFRJ)
Av. Athos da Silveira Ramos, 149 - CT - Bl A - sala 547
CEP 21941-909
Rio de Janeiro - RJ
Brazil